Back in 2012 I posted a blog titled PC Maintenance where I outlined what I did to maintain my computers. I do the same today with two additions.
1. I use Glary Utilities for a quick check as often as every day (when I remember!) Download it at http://www.glarysoft.com/
2. I use EaseUS to do an image backup of each computer to an external hard drive at least once a month. I let Mozy or iDrive backup my critical files that are changing on a daily basis. So between the two backsup I can totally recover from any system failure.
Here is the original post:
Here is post on Backing Up with Mozy and EaseUS:
And one on iDrive: